Multiple organ dysfunction syndrome mods is altered organ function in an acutely ill patient requiring medical intervention to achieve homeostasis although irwin and rippe caution in 2005 that the use of multiple organ failure or multisystem organ failure should be avoided both harrisons 2015 and cecils 2012 medical textbooks still use the terms multi organ failure and . Multiple organ failure multiple organ failure mof is a severe life threatening condition that usually occurs as a result of major trauma burns or fulminant infections whatever the initiating event once established mof has a high mortality up to 80 the pathophysiological mechanisms underlying this condition are unclear although important contributory factors probably include hypoxia increased intestinal permeability bacterial translocation endotoxemia and uncontrolled . Multiple organ dysfunction syndrome mods also called multi organ failure multiple systems organ failure or through some of its more prominent manifestations as the acute respiratory distress syndrome ards or disseminated intravascular coagulation dic is one of the most common syndromes of critical illness and the leading cause of mortality among critically ill patients 1
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